abstract：BACKGROUND AND AIMS:The occurrence of reflux disease seems to be rising in the United States. The aim of the present study was to follow the time trends of hospitalization for gastroesophageal reflux disease (GERD) and other esophageal disease during the past 4 decades. METHODS:US hospital utilization data were availa...

journal_title：Journal of clinical gastroenterology

authors： Sonnenberg A

更新日期：2014-09-01 00:00:00

abstract：:Practitioners of endoscopy often experience musculoskeletal pain and injury (most often in the back, neck, shoulders, hands, wrists, and thumbs) that are associated with the minute and repetitive strain that is placed on these areas during endoscopic procedures. This review of the current documentation of endoscopy-re...

journal_title：Journal of clinical gastroenterology

authors： Harvin G

更新日期：2014-08-01 00:00:00

abstract：:Inflammatory bowel disease (IBD) is a chronic relapsing disorder of the intestine of unclear etiology. Increasing evidence has pointed to intestinal dysbiosis as a potential factor in a genetically susceptible individual. Fecal microbiota transplantation (FMT) has been used to treat inflammatory bowel disease with var...

journal_title：Journal of clinical gastroenterology

authors： Kao D,Hotte N,Gillevet P,Madsen K

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:There are few data regarding the prevalence of hepatitis-B virus (HBV) markers in inflammatory bowel disease (IBD) patients in Korea, which is a hepatitis-B-endemic area. The aim of this study was to assess the prevalence of HBV markers in IBD patients in comparison with controls. METHODS:We enrolled 513 IB...

journal_title：Journal of clinical gastroenterology

authors： Kim ES,Cho KB,Park KS,Jang BI,Kim KO,Jeon SW,Kim EY,Yang CH,Kim WJ,Daegugyeongbuk Gastrointestinal Study Group (DGSG).

更新日期：2014-07-01 00:00:00

abstract：GOALS:We aimed to quantify pharyngeal exposure to gastric contents in patients diagnosed with reflux-related hoarseness and healthy controls using new diagnostic techniques. BACKGROUND:Hoarseness with typical signs on laryngoscopy is commonly thought to be caused by esophagopharyngeal reflux. New methods are proposed ...

journal_title：Journal of clinical gastroenterology

authors： Hayat JO,Yazaki E,Moore AT,Hicklin L,Dettmar P,Kang JY,Sifrim D

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND AND AIM:Intestinal fatty acid-binding protein (I-FABP) is a useful marker in the detection of intestinal ischemia. However, more insight into the test characteristics of I-FABP release is needed. This study aimed to investigate the relationship between plasma I-FABP levels and the severity of ischemic mucosa...

journal_title：Journal of clinical gastroenterology

authors： Schellekens DH,Grootjans J,Dello SA,van Bijnen AA,van Dam RM,Dejong CH,Derikx JP,Buurman WA

更新日期：2014-03-01 00:00:00

abstract：INTRODUCTION:Whether body position affects lower esophageal sphincter (LES) function and detection of hiatal hernia is unknown. Moreover, the yield of high-resolution esophageal pressure topography (HREPT) when compared with endoscopy for detection of hiatal hernia is unclear. AIM:The aims of this study were to examin...

journal_title：Journal of clinical gastroenterology

authors： Hashmi S,Rao SS,Summers RW,Schulze K

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND AND GOAL:Peribiliary cysts, which are known to be associated with various hepatobiliary diseases including alcoholic liver disease, have been reported to originate in the peribiliary glands along the biliary tree. The causal relationship between the peribiliary cysts and alcohol-related hepatic and pancreati...

journal_title：Journal of clinical gastroenterology

authors： Matsubara T,Sato Y,Igarashi S,Matsui O,Gabata T,Nakanuma Y

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:The metabolic syndrome (MetS) and/or its individual components have been linked to the development of cancer. Recent studies have suggested a similar link to hepatocellular carcinoma (HCC). The aim of this study was to evaluate the direction and magnitude of the association between the MetS and HCC. METHODS...

journal_title：Journal of clinical gastroenterology

authors： Jinjuvadia R,Patel S,Liangpunsakul S

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Inactive and active phases of hepatitis B e antigen-negative chronic hepatitis B virus (HBV) infection are diagnosed by serum HBV DNA levels, with cutoff at 2000 IU/mL. However, it is difficult to distinguish inactive carriers at a single time point because HBV DNA levels can transiently decrease to <2000 IU...

journal_title：Journal of clinical gastroenterology

authors： Yim SY,Um SH,Jung JY,Seo YS,Yim HJ,Ryu HS,Chun HJ,Jeen YT,Kim CD,Keum B,Lee HS

更新日期：2014-02-01 00:00:00

abstract：:Gastroesophageal reflux disease, especially when refractory to standard therapy, remains a significant clinical problem. Although symptom pathogenesis in erosive reflux disease is relatively easy to understand, it is less clear how exposure of the macroscopically normal mucosa in nonerosive reflux disease (NERD) is ab...

journal_title：Journal of clinical gastroenterology

authors： Woodland P,Sifrim D

更新日期：2014-01-01 00:00:00

abstract：GOALS:To evaluate the incidence of extraesophageal malignancies among patients with Barrett esophagus (BE). BACKGROUND:Gastroesophageal reflux disease has been reported to be associated with upper aerodigestive malignancies. BE is considered a consequence of long-standing gastroesophageal reflux disease; however, the ...

journal_title：Journal of clinical gastroenterology

authors： Pines G,Dickman R,Niv Y,Kashtan H,Birkenfeld S

更新日期：2014-01-01 00:00:00

abstract：GOALS:To describe current hepatitis C virus (HCV) treatment practices in the United States and identify physician characteristics associated with the use of first generation direct-acting antivirals (DAAs). BACKGROUND:HCV treatment practice patterns have not been assessed after the introduction of DAA, which are now c...

journal_title：Journal of clinical gastroenterology

authors： Chen EY,Lee WM,Hynan LS,Singal AG

更新日期：2013-10-01 00:00:00

abstract：GOALS:To estimate the hepatocellular carcinoma surveillance in the Medicaid cirrhotic population. BACKGROUND:Most studies predate 2005 American Association for the Study of Liver Diseases surveillance recommendations and do not examine the primary target population, cirrhotics. STUDY:From 2006 to 2007, we identified ...

journal_title：Journal of clinical gastroenterology

authors： Palmer LB,Kappelman MD,Sandler RS,Hayashi PH

更新日期：2013-09-01 00:00:00

abstract：GOALS:We determined yearly rates of upper and lower gastrointestinal (GI) hospitalizations in Quebec, Canada and compared the 1-year readmission and mortality risks among those discharged from lower versus upper GI hospitalizations. BACKGROUND:The burden of serious upper and lower GI events is substantial. STUDY:Demo...

journal_title：Journal of clinical gastroenterology

authors： Rahme E,Roussy JP,Woolcott J,Nedjar H,Barkun A

更新日期：2013-08-01 00:00:00

abstract：:Despite the successful FDA approval of sorafenib as the standard of care therapy in patients with advanced hepatocellular carcinoma (HCC), its clinical benefits have been modest. The mortality rate remains high and prognosis poor for patients with advanced-stage HCC. The exact mechanism of sorafenib in the treatment o...

journal_title：Journal of clinical gastroenterology

authors： Lee JK,Abou-Alfa GK

更新日期：2013-07-01 00:00:00

abstract：:Image-guided percutaneous local and regional modalities are major treatments for hepatocellular carcinoma. Patients having better liver function and performance are usually eligible and can gain significant survival benefit, especially with more limited tumor burden. The most common local therapies are ethanol and rad...

journal_title：Journal of clinical gastroenterology

authors： Pollak JS

更新日期：2013-07-01 00:00:00

abstract：GOALS:We investigated the prognosis of Crohn's disease (CD) in Korean patients with jejunal involvement. BACKGROUND:Although jejunal involvement is considered a poor prognostic factor of CD in whites, it has never been validated in Asian populations. METHODS:We retrospectively reviewed the medical records of 1403 Kor...

journal_title：Journal of clinical gastroenterology

authors： Park SK,Yang SK,Park SH,Park SH,Kim JW,Yang DH,Jung KW,Kim KJ,Ye BD,Byeon JS,Myung SJ,Yu CS,Kim JH

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Guidelines for chronic hepatitis C virus (HCV) management have recommended that a liver biopsy be repeated at 3-year intervals for HIV/HCV-coinfected patients and 5-year intervals for those with HCV monoinfection to assess fibrosis progression. However, it is unclear if patients are willing to repeat this pr...

journal_title：Journal of clinical gastroenterology

authors： Amorosa VK,Aibana O,Shire NJ,Dorey-Stein Z,Ferrara T,Gilmore J,Kostman JR,Lo Re V 3rd

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND/GOALS:The endoscopic treatment of ampullary adenomas is established; however, the false-negative rate of endoscopic biopsy for carcinoma is 20% to 30%, and it remains uncertain whether identifiable features predict malignancy. Our aim in this study was to evaluate the predictable factors of malignancy in amp...

journal_title：Journal of clinical gastroenterology

authors： Kim HN,Kim KM,Shin JU,Lee JK,Lee KT,Lee KH,Kim KM,Lim JH

更新日期：2013-04-01 00:00:00

abstract：:It is becoming increasingly recognized that purely clinical endpoints may not be sufficient in the treatment of patients with inflammatory bowel disease. As such, mucosal disease assessment has become a prominent component of the majority of recent clinical trials in Crohn's disease and ulcerative colitis. There is mo...

journal_title：Journal of clinical gastroenterology

authors： Osterman MT

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND/AIMS:The aim of this exploratory trial was to establish if the probiotic Bifidobacterium natren life start (NLS) strain strain may affect the clinical course and pathophysiological features of patients with untreated celiac disease (CD). Positive findings would be helpful in directing future studies. METHOD...

journal_title：Journal of clinical gastroenterology

authors： Smecuol E,Hwang HJ,Sugai E,Corso L,Cherñavsky AC,Bellavite FP,González A,Vodánovich F,Moreno ML,Vázquez H,Lozano G,Niveloni S,Mazure R,Meddings J,Mauriño E,Bai JC

更新日期：2013-02-01 00:00:00

abstract：GOALS:To analyze the neurochemical profile during the recurrent attacks of nausea and vomiting in patients with Riley-day syndrome. BACKGROUND:One of the most disabling features of patients with Riley-day syndrome are recurrent attacks of severe nausea/retching/vomiting accompanied by hypertension, tachycardia, and sk...

journal_title：Journal of clinical gastroenterology

authors： Norcliffe-Kaufmann LJ,Axelrod FB,Kaufmann H

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:There has been constant speculation about the association between metabolic syndrome (MetS) and colorectal neoplasia (CN); however, the published results are conflicting. The aims of this study are to conduct a systematic search, and assess the literature to determine the available evidence on the associatio...

journal_title：Journal of clinical gastroenterology

authors： Jinjuvadia R,Lohia P,Jinjuvadia C,Montoya S,Liangpunsakul S

更新日期：2013-01-01 00:00:00

abstract：GOALS/BACKGROUND:The importance of hepatitis B virus (HBV) genotype and mutations has been increasingly recognized. We aimed to determine HBV genotype, precore (PC), and basal core promoter region (BCP) mutations in a HBV multiethnic South Florida population. STUDY:Samples from 213 patients were tested for HBV-DNA usi...

journal_title：Journal of clinical gastroenterology

authors： Couto CA,Levy C,Morris CJ,Hill M,de Medina M,Sanborn MR,Cloherty GA,Schiff ER,Martin P

更新日期：2013-01-01 00:00:00

abstract：GOALS:We evaluated the efficacy of initial and follow-up hepatic venous pressure gradient (HVPG), models of end-stage liver disease (MELD), and MELD-Na for predicting the survival of patients with decompensated liver cirrhosis (LC). BACKGROUND:MELD with/without Na score and HVPG have been important predictors of morta...

journal_title：Journal of clinical gastroenterology

authors： Suk KT,Kim CH,Park SH,Sung HT,Choi JY,Han KH,Hong SH,Kim DY,Yoon JH,Kim YS,Baik GH,Kim JB,Kim DJ

更新日期：2012-11-01 00:00:00

abstract：:Eosinophilic esophagitis (EoE) is a chronic, immune/antigen-mediated, esophageal disease characterized by esophageal dysfunction and eosinophilic inflammation, manifested mainly as dysphagia and frequent food impaction. EoE is recognized into the spectrum of food allergy, but food sensitization studies used not to be ...

journal_title：Journal of clinical gastroenterology

authors： González-Cervera J,Angueira T,Rodriguez-Domínguez B,Arias A,Yagüe-Compadre JL,Lucendo AJ

更新日期：2012-11-01 00:00:00

abstract：:The intestinal barrier serves 2 critical functions for the survival of the individual: first, it allows nutrient absorption and second, it defends the body from dangerous macromolecule penetration. It is a complex multilayer system, consisting of an external "anatomic" barrier and an inner "functional" immunological b...

journal_title：Journal of clinical gastroenterology

authors： Scaldaferri F,Pizzoferrato M,Gerardi V,Lopetuso L,Gasbarrini A

更新日期：2012-10-01 00:00:00

abstract：AIM:To test the activities of culture-extracted or commercially available toll-like receptors (TLRs) ligands to establish their direct impact on target gastrointestinal motor cells. METHODS:Short-term and long-term effects of Shigella flexneri M90T and Escherichia coli K-2 strains-extracted lipopolysaccharides (LPS), ...

journal_title：Journal of clinical gastroenterology

authors： Tattoli I,Petitta C,Scirocco A,Ammoscato F,Cicenia A,Severi C

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Hypoxic hepatitis (HH) occurring after gastrointestinal bleeding in cirrhotic patients has been scarcely studied and is reported as a rare occurrence carrying a severe prognosis. The management of bleeding from esophageal varices (BEV) and similarly the prognosis has improved in the last decades. GOALS:To e...

journal_title：Journal of clinical gastroenterology

authors： Amitrano L,Guardascione MA,Martino R,Manguso F,Menchise A,Balzano A

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Nighttime reflux has been demonstrated to be associated with a more aggressive presentation of gastroesophageal reflux disease (GERD). However, it has remained unknown until now if the difference in nighttime reflux between the different GERD groups is related to the distribution of intraesophageal pH level ...

journal_title：Journal of clinical gastroenterology

authors： Hershcovici T,Jha LK,Fass R

更新日期：2012-08-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is the most common cause of liver disease in adults and children and is currently the third most common indication for liver transplantation in North America. Its pathogenesis is thought to be secondary to multiple "hits" derived from the dietary components, adipose tissue, imm...

journal_title：Journal of clinical gastroenterology

authors： Mouzaki M,Allard JP

更新日期：2012-07-01 00:00:00

abstract：GOALS:To evaluate management, outcome, and follow-up of patients with sporadic duodenal adenomas and assess the presence of colorectal neoplasms. BACKGROUND:With the widespread use of esophagogastroduodenoscopy, an increasing number of sporadic duodenal adenomas are diagnosed. An optimal algorithm for management has n...

journal_title：Journal of clinical gastroenterology

authors： van Heumen BW,Mul K,Nagtegaal ID,van Kouwen MC,Nagengast FM

更新日期：2012-05-01 00:00:00

abstract：GOALS:To determine whether the presence of dupA Helicobacter pylori (H. pylori) influences the cure rate of primary eradication therapy. BACKGROUND:Several virulence factors of H. pylori have been reported to affect the efficacy of the eradication rate. However, no study has investigated whether the presence of dupA a...

journal_title：Journal of clinical gastroenterology

authors： Shiota S,Nguyen LT,Murakami K,Kuroda A,Mizukami K,Okimoto T,Kodama M,Fujioka T,Yamaoka Y

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:The clinical effect of probiotics on irritable bowel syndrome (IBS) is still controversial. AIMS:We aimed to evaluate the effects of a probiotic mixture on IBS symptoms and the composition of fecal microbiota in patients with diarrhea-dominant IBS (D-IBS). METHODS:Fifty patients with D-IBS were randomized ...

journal_title：Journal of clinical gastroenterology

authors： Ki Cha B,Mun Jung S,Hwan Choi C,Song ID,Woong Lee H,Joon Kim H,Hyuk J,Kyung Chang S,Kim K,Chung WS,Seo JG

更新日期：2012-03-01 00:00:00

abstract：:Bleeding caused by ectopic varices is an uncommon but important and life-threatening complication of portal hypertension. Spontaneous external hemorrhage from a recanalized umbilical varix is an extremely rare source of ectopic variceal bleeding. We report on the acute presentation of a patient with a bleeding umbilic...

journal_title：Journal of clinical gastroenterology

authors： Assis DN,Pollak J,Schilsky ML,Emre S

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND AIM:Voice-related complaints are the most common extraesophageal manifestation of gastroesophageal reflux disease (GERD). The aim of this study was to compare objectively measured voice parameters in normal subjects and patients with GERD and to assess the impact of antireflux surgery on these parameters...

journal_title：Journal of clinical gastroenterology

authors： Ayazi S,Pearson J,Hashemi M

更新日期：2012-02-01 00:00:00

abstract：GOALS:To evaluate the impact of age on the prognosis of patients with hepatocellular carcinoma (HCC) undergoing percutaneous radiofrequency ablation (RFA). BACKGROUND:Whether age plays an important role in the outcomes of HCC after RFA remains controversial. STUDY:Two hundred fifty-eight consecutive treatment naive H...

journal_title：Journal of clinical gastroenterology

authors： Kao WY,Chiou YY,Hung HH,Su CW,Chou YH,Huo TI,Huang YH,Wu WC,Lin HC,Lee SD,Wu JC

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:It remains controversial whether or not cytomegalovirus infection in patients with active ulcerative colitis reflects a nonpathogenic colonization or a pathogenic disease warranting antiviral therapy. GOALS:The aim of this study was to determine the prevalence of cytomegalovirus infection in patients with a...

journal_title：Journal of clinical gastroenterology

authors： Kim YS,Kim YH,Kim JS,Cheon JH,Ye BD,Jung SA,Park YS,Choi CH,Jang BI,Han DS,Yang SK,Kim WH,IBD Study Group of the Korean Association for the Study of Intestinal Diseases.

更新日期：2012-01-01 00:00:00

abstract：:Sjogren syndrome (SS) is an autoimmune disease that affects exocrine glands and therefore may affect the gastrointestinal system, from the mouth, esophagus, and bowel to the liver and pancreas. Oral involvement in SS is mainly characterized by dryness, with a wide spectrum of symptoms, from mild-to-severe xerostomia w...

journal_title：Journal of clinical gastroenterology

authors： Ebert EC

更新日期：2012-01-01 00:00:00